Here is the keymap I'm using on my Microdox.
Some ideas behind the layout were:
Keep everything nicely grouped.
There is a nav layer with all the navkeys on the right hand, a symbol layer with everything grouped on the left.
The thumb activating a layer shouldn't do too much.
The left thumb activates the navigation layer while the right hand does all the navigating, the left hand has only modifiers. On other layers, those roles are reversed, but the idea remains the same.
While I prefer my own weird little layout, the Miryoku keymap has some great principles behind the keymap.
Especially the 2nd point is heavily inspired by Miryoku. It makes one-handed use pretty much impossible, but that happens very rarely in my daily usage.
microdox - BASE
Hover over layer-keybinds to see which layer gets activated